N-acetylcysteine modulates angiogenesis and vasodilation in stomach such as DNA damage in blood of portal hypertensive rats

Figure 2 Immunohistochemistry for endothelial nitric oxide synthase, vascular endothelial growth factor and nitrotyrosine. A: Effects of partial portal vein ligation (PPVL) and N-acetylcysteine (NAC) administration on eNOS immunoreactivity in gastric mucosa, ^bP < 0.001 (n = 6); B: Effects of partial PPVL and NAC administration on VEGF immunoreactivity in gastric mucosa, ^aP < 0.05 (n = 6); C: Effects of PPVL and NAC administration on NTT immunoreactivity in gastric mucosa, ^aP < 0.05 (n = 6). SO: Sham-operated group; PPVL: Partial portal vein ligation group; PPVL + NAC: Partial portal vein ligation group treated with NAC. Original magnification × 400.