Treatment-related gastrointestinal toxicities and advanced colorectal or pancreatic cancer: A critical update

Table 1 Oral mucositis grading scales

CTCAE version 4.03	Grade
	1	2	3	4	5
Description	Asymptomatic or mild symptoms; intervention not indicated	Moderate pain; not interfering with oral intake; modified diet indicated	Severe pain; interfering with oral intake	Life-threatening consequences; urgent intervention indicated	Death
WHO	Grade
	0 (none)	I (mild)	II (moderate)	III (severe)	IV (life-threatening)
Description	None	Oral soreness, erythema	Oral erythema, ulcers, solid diet tolerated	Oral ulcers, liquid diet only	Oral alimentation impossible

CTCAE: Common Terminology Criteria for Adverse Events version; WHO: World Health Organization.