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Copyright ©The Author(s) 2015.
World J Gastroenterol. Nov 7, 2015; 21(41): 11567-11583
Published online Nov 7, 2015. doi: 10.3748/wjg.v21.i41.11567
Table 1 Diagnostic accuracy of established serum markers
TestParametersPrognosisSensitivitySpecificityAUROC
APRIAST, platelet countSignificant fibrosis81550.77
Cirrhosis77750.84
FIB-4Platelet count, AST, ALT, ageSignificant fibrosis64680.74
Cirrhosis90580.87
FibrotestHaptoglobin, α2-macroglobulin, apolipoprotein A1, γGT, bilirubinSignificant fibrosis92380.79
Cirrhosis83760.86
Forns IndexAge, platelet count, γGT, cholesterolSignificant fibrosis88520.76
Cirrhosis98270.87
HAhyaluronanSignificant fibrosis--0.75
Cirrhosis165860.92
HepaScoreBilirubin, γGT, hyaluronan, α2-macroglobulin, age, genderSignificant fibrosis66790.79
Cirrhosis72860.89
FibrometerPlatelet count, prothrombin index, AST, α2-macro-globulin, hyaluronan, urea, ageSignificant fibrosis69810.82
Cirrhosis162870.90