Are faecal markers good indicators of mucosal healing in inflammatory bowel disease?

Table 6 Studies investigating the correlation between other faecal marker concentrations and histologic activity in subjects with inflammatory bowel diseases

Ref.	Number of participants		Population	Histology index used	Histology indexcut off	Faecal marker measured	Faecal marker cut off	Outcome measures				Correlation
	CD	UC						Sensitivity	Specificity	PPV	NPV	r value	P value
Crohn’s disease studies
Kaiser et al[42]	32	27	Adults	Unique score	0	S100A12		-	-	-	-	0.44	< 0.01
	32					S100A12	0.8	81	100	-	-	0.451	0.01
		27				S100A12	0.8	91	100	-	-	0.44	< 0.025

CD: Crohn’s disease; UC: Ulcerative colitis; PPV: Positive predictive value; NPV: Negative predictive value.