Vitamin D status and viral response to therapy in hepatitis C infected children

Table 4 Mean ± SD values of laboratory parameters in relation to Vitamin D status in the studied groups

	Vitamin D status			Control (n = 28)	Suff vs Insuff	Suff vs Def	Insuff vsDef	Total P value
	Sufficient (n = 14)	Insufficient (n = 26)	Deficient (n = 20)
ALT (IU/L)	97.643 ± 18.06	75.654 ± 15.954	78.45 ± 17.824	21.35 ± 6.21	0.327	0.475	0.885	0.610
AST (IU/L)	97.786 ± 24.215	94.923 ± 13.151	77.4 ± 13.363	35.74 ± 4.92	0.934	0.453	0.551	0.772
Calcium (mg/dL)	7.993 ± 1.183	7.023 ± 1.396	6.13 ± 1.185	8.2 ± 0.91	0.769	0.031	0.090	0.077
Phosphorus (mg/dL)	3.31 ± 0.25	4.21 ± 0.31	4.24 ± 0.61	3.1 ± 0.65	0.354	0.412	0.614	0.456
Alkaline phosphatase (IU/L)	82.92 ± 15.62	109.34 ± 13.08	159.96 ± 14.64	78.48 ± 21.10	0.493	0.068	0.233	0.192
HCV RNA(IU/mL)	1300824 ± 664010	1417943 ± 137873	787100 ± 65915	10.21 ± 0.74	0.705	0.031	0.0221	0.0432
Vitamin D (nmol/L)	84.21 ± 17.821	49.23 ± 15.07	22.6 ± 3.858	98.31 ± 3.50	0.0001	0.001	0.0001	0.0012
PTH (pg/mL)	128.53 ± 20.37	164.05 ± 12.63	179.46 ± 19.24	65.71 ± 12.05	0.181	0.322	0.607	0.296

¹Significance between groups vs control;

²Significance total vs control. AST: Aspartate transaminase; ALT: Alanine transaminase; PTH: Parathormone; Suff: sufficient; Insuff: Insufficient; Def: Deficient.