Dimethyl sulfoxide inhibits zymosan-induced intestinal inflammation and barrier dysfunction

Figure 6 Gut injury scores. Gut injury was scored by a pathologist blinded to the experimental groups on a scale of 0-4, (as described in Materials and Methods). ^aP < 0.05 vs group SS and group SD, ^bP < 0.05 vs group ZS (n = 8 per group at 4, 8, and 24 h after intraperitoneal injection of zymosan). DMSO: Dimethyl sulfoxide; SS: Sham with administration of normal saline; SD: Sham with administration of DMSO; ZS: Zymosan with administration of normal saline; ZD: Zymosan with administration of DMSO.