Influence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer

Figure 3 Association of the rs2736100 polymorphism with hTERT mRNA expression and telomere length in 35 gastric cancers. A: The genotype of rs2736100 polymorphism of the hTERT gene was closely associated with hTERT mRNA expression and telomere length (P = 0.0026 and P = 0.0199, respectively); B: When we combined C/A and A/A genotypes, the cases carrying the A allele (A/A and C/A genotypes) showed lower hTERT mRNA expression levels and shortened telomere length, compared with those who had C/C homozygote genotype (P = 0.0016 and P = 0.0098, respectively). hTERT: Human telomerase reverse transcriptase.