High expression of CD11c indicates favorable prognosis in patients with gastric cancer

Table 4 Multivariate Cox model analysis of the association between CD11c expression and the risk of death and relapse n (%)

Clinicopathological parameters	Number	OS			DFS
		HR	95%CI	P value	HR	95%CI	P value
CD11C expression
Low	109 (77.86)	1.00 (ref)			1.00 (ref)
High	31 (22.14)	0.56	0.33-0.98	0.041	0.39	0.23-0.67	0.001
Gender
Male	107 (76.43)	1.00 (ref)			1.00 (ref)
Female	33 (23.57)	1.08	0.64-1.83	0.769	0.77	0.46-1.27	0.306
Age groups
About 45	12 (8.57)	1.00 (ref)			1.00 (ref)
About 60	66 (47.14)	0.52	0.25-1.08	0.080	0.51	0.26-1.03	0.060
> 60	62 (44.29)	0.82	0.39-1.73	0.608	0.70	0.35-1.41	0.316
Gastric cardia
No	87 (62.14)	1.00 (ref)			1.00 (ref)
Yes	53 (37.86)	1.58	1.02-2.43	0.039	1.42	0.95-2.11	0.085
Histological type%
Differentiated	54 (40.60)	1.00 (ref)			1.00 (ref)
Poorly differentiated	79 (59.40)	1.26	0.79-2.02	0.333	1.025	0.68-1.56	0.907
Pathological grade
1-2	17 (12.14)	1.00 (ref)			1.00 (ref)
3	70 (50.00)	0.79	0.35-1.76	0.564	0.85	0.41-1.75	0.659
4	53 (37.86)	1.08	0.47-2.48	0.849	1.32	0.63-2.79	0.466
UICC stage
I	11 (7.86)	1.00 (ref)			1.00 (ref)
II	27 (19.20)	2.90	0.74-11.32	0.126	1.99	0.65-6.10	0.230
III	88 (62.86)	3.36	0.91-12.39	0.069	2.12	0.74-6.10	0.162
IV	14 (10.00)	9.94	2.46-40.19	0.001	9.20	2.75-30.78	< 0.001

OS: Overall survival; DFS: Disease-free survival.