Transient elastography improves detection of liver cirrhosis compared to routine screening tests

Table 5 Usefulness of transient elastography in cirrhotic patients with Child-Pugh A or normal platelet count

	Child-Pugh A1					Normal platelet count2
	Sensitivity	Specificity	PPV	NPV	P value3	Sensitivity	Specificity	PPV	NPV	P value3
Liver stiffness ≥ 13 kPa	91.5%	48.8%	59.5	87.5		85.3%	62.4%	66.7	82.8
Ultrasound	75.2%	75.2%	72.5	77.8	0.02	71.2%	86.4%	82.5	76.9	0.04
Platelets < 150.000/μL	55.1%	78.6%	68.6	67.3	NS	NA	NA	NA	NA
Cutaneous liver signs	42.0%	74.8%	59.2	59.7	0.01	46.2%	81.3%	66.7	65.0	0.001

¹n = 107;

²n = 161; Normal platelet count was 150.000-400.000/μL;

³Values are given for the comparison of sensitivities with transient elastography. NA: Not applicable; NS: Not significant; PPV: Positive predictive value; NPV: Negative predictive value.