Clinical Trials Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jul 21, 2015; 21(27): 8398-8407
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8398
Table 6 Univariate analysis of factors influencing overall survival in 402 patients with gastrointestinal stromal tumor
Factor5-yr OS rate (%)OS HR (95%CI)P value
GenderMale: Female81.3: 89.20.508 (0.221-1.169)0.111
Age (yr) ≤ 60: > 6088.9: 80.02.186 (0.989-4.832)0.053
Gastrointestinal bleedingNo: Yes86.8: 81.21.259 (0.559-2.837)0.578
Primary tumor siteGastric: Non-gastric83.0: 86.81.143 (0.529-2.470)0.733
Predominant cell typeSpindle: Epithelioid: Mixed87.7: 82.4: 88.80.935 (0.586-1.491)0.778
Primary tumor size (cm) ≤ 5: > 599.2: 74.022.726 (3.079-167.742)0.0021
Mitotic index (HPFs) ≤ 5/50: 6-10/50: > 10/5096.5: 83.0: 39.74.727 (2.887-7.740)< 0.0011
NIH stageVery low: Low: Mid: High100.0: 100.0: 88.6: 70.38.005 (2.365-27.098)0.0011
SLITRK3 expression(-): (+): (++): (+++)100.0: 99.0: 86.7: 57.44.164 (2.227-7.786)< 0.0011