Diagnostic performance of magnifying narrow-band imaging for early gastric cancer: A meta-analysis

Table 1 Characteristics of the selected studies

Ref.	No. of patients	Sex,male/female	Age, mean	Country	Diagnostic standard	Morphology type of lesions (depressed/not depressed)	Lesion size (mm)	Type of assessment	Endoscopic system (Lucera/Exera)	Endoscopists number
Liu et al[19]	90	49/41	57.5	China	Type1 A-E	47/160	NA	Real-time	NA	2
Yao et al[20]	310	183/127	66	Japan	Irregular MV and/or irregular MS with a demarcation line	231/134	NA	Real-time	Lucera	20
Kanesaka et al[21]	49	35/16	NA	Japan	Presence of dense-type crypt openings	0/51	NA	Post-procedure	Lucera	4
Tao et al[4]	508	316/192	63	China	Irregular MV and/or irregular MS with a demarcation line	192/451	7	Post-procedure	NA	NA
Horiuchi et al[22]	51	31/20	65	Japan	Micrification of fine mucosal structure	0/64	NA	Post-procedure	Lucera	NA
Maki et al[5]	93	73/20	NA	Japan	Irregular MV and/or irregular MS with a demarcation line	0/93	NA	Post-procedure	Lucera	NA
Miwa et al[6]	135	77/58	70.1	Japan	Irregular MV and/or irregular MS with a demarcation line	26/109	NA	Post-procedure	Lucera	NA
Tsuji et al[24]	137	101/36	NA	Japan	Irregular MV and/or irregular MS with a demarcation line	19/118	NA	Post-procedure	Lucera	4
Li et al[23]	146	88/58	59.3	China	Type2 A-C	52/112	21.9	Real-time	Lucera	2
Ezoe et al[3]	353	278/75	69	Japan	Irregular MV with a demarcation line	353/0	5.6	Real-time	Lucera	31
Nonaka et al[25]	93	71/22	70	Japan	Type3 I-V	0/93	15.1	Real-time	NA	4
Ezoe et al[7]	53	NA	NA	Japan	Irregular MV with a demarcation line	57/0	≤ 10	Real-time	Lucera	5
Kato et al[8]	111	98/13	66.3	Japan	Disappearance of fine mucosal structure, microvascular dilation, heterogeneity	NA	7.0	Real-time	Lucera	NA
Yao et al[26]	42	NA	NA	Japan	Either WOS with a regular distribution or a regular MV	0/46	NA	Real-time	Lucera	1

¹Type A-E: Type A, short rod-like pits with regular microvasculature inside pits; Type B, elongated open branch-like pits with regular microvasculature; Type C, dilated pits and increased branching microvasculature; Type D, villus-like appearance or light blue crest sign; Type E, the appearance of new tumor vessels;

²Type A-C: Type A, clear regular surface patterns and microvascular architecture; Type B, obscure irregular surface patterns or microvascular architecture; Type C, no surface pattern and sparse microvessels or with avascular areas;

³Type I-V: Type I, clear MS, unclear MV; type II, clear MS, clear MV; type III, clear MS, abnormal MV; type IV, slightly obscured MS, abnormal MV; type V, markedly obscured MS, abnormal MV. NA: Not available; MV: The microvascular pattern; MS: The microsurface pattern; WOS: White opaque substance.