Protective effect of bicyclol against bile duct ligation-induced hepatic fibrosis in rats

Figure 4 Effects of bicyclol on the fibrogenic gene expression. The mRNA expression levels were assayed by reverse transcription quantitative-polymerase chain reaction with TaqMan gene expression kits (A), Western blot analysis of α-smooth muscle actin (α-SMA) and transforming growth factor (TGF)-β1/2 expression in each bile duct ligation (BDL) rat liver (B) and normalized against Gapdh. Data are expressed as mean ± SD of 6 animals per group. ^aP < 0.05 vs Sham group; ^cP < 0.05 vs BDL group. Sham: Sham group; BDL: BDL group; BDL-Bic: Bicyclol group.