Efficacy of poly-unsaturated fatty acid therapy on patients with nonalcoholic steatohepatitis

Table 3 Histological evaluation at initial evaluation and 6 mo later

Variables	Controlled	PUFA	P value
At the initial evaluation
Steatosis grade	1.8 ± 0.2	1.9 ± 0.2	0.355
Necro-inflammatory grade	1.4 ± 0.2	1.4 ± 0.1	0.268
Fibrosis stage	1.7 ± 0.2	1.7 ± 0.1	0.309
Ballooning score	1.6 ± 0.3	1.6 ± 0.2	0.227
Six months later
Steatosis grade	1.8 ± 0.1	1.4 ± 0.2	0.032
Necro-inflammatory grade	1.5 ± 0.1	1.1 ± 0.1	0.017
Fibrosis stage	1.6 ± 0.3	1.1 ± 0.2	0.020
Ballooning score	1.6 ± 0.2	1.0 ± 0.2	0.015

PUFA: Poly-unsaturated fatty acid.