Increased density of tolerogenic dendritic cells in the small bowel mucosa of celiac patients

Figure 7 Mean values of CD11c⁺, IDO⁺, CD103⁺ and Langerin⁺ DCs in celiac disease patients are significantly higher compared with these values in persons with normal small bowel mucosa (according to the immunofluorescence data from cryostat sections). Columns represent the mean values of positively stained cells per microscopic field in patients with CD vs patients with normal mucosa. ^bP < 0.01, CD11c⁺ in patients with CD vs patients with normal mucosa; ^dP < 0.01, IDO⁺ in patients with CD vs patients with normal mucosa; ^fP < 0.01, CD103⁺ in patients with CD vs patients with normal mucosa; ^aP < 0.05, Langerin⁺ CD103⁺ in patients with CD vs patients with normal mucosa. CD: Celiac disease; IDO: Indoleamine 2,3-dioxygenase; DC: Dendritic cell.