Clinicopathologic factors and molecular markers related to lymph node metastasis in early gastric cancer

doi:10.3748/wjg.v21.i2.571

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Jan 14, 2015 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2015; 21(2): 571-577
Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.571

Table 2 Molecular markers of patients with early gastric cancer n (%)

Molecular markers	Value
Microsatellite instability
MSS	909 (90.1)
MSI-L	31 (3.1)
MSI-H	69 (6.8)
hMLH1
Loss	48 (6.3)
Expression	716 (93.7)
p53
Negative	651 (62.2)
Positive	396 (37.8)
EGFR overexpression
Negative	613 (88.8)
Positive	77 (11.2)
HER2 overexpression
Negative	296 (72.9)
Positive	110 (27.1)

MSS: Microsatellite stable; MSI-L: Microsatellite instability-low; MSI-H: Microsatellite instability-high; hMLH1: Human mutL homolog 1; EGFR: Epidermal growth factor receptor; HER2: Human epidermal growth factor receptor 2.

Citation: Jin EH, Lee DH, Jung SA, Shim KN, Seo JY, Kim N, Shin CM, Yoon H, Jung HC. Clinicopathologic factors and molecular markers related to lymph node metastasis in early gastric cancer. World J Gastroenterol 2015; 21(2): 571-577
URL: https://www.wjgnet.com/1007-9327/full/v21/i2/571.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i2.571