Endoscopic submucosal dissection for early gastric cancer with undifferentiated-type histology: A meta-analysis

Table 1 Clinical data of included studies

Ref.	Duration of follow up	Location, language	Complete resection	Curative resection	En bloc resection	Total recurrence	Adverse events	Total patients
Kim et al[23], 2009	Mean 17.1 ± 9.1 mo	South Korea (English)				1/32	Bleeding 6/32	32
Kang et al[24], 2010	Mean 16 mo	South Korea (English)	33/60		60/60	0/60	Bleeding 1/60 perforation 1/60	60
Lee et al[25], 2010	Median 13.5 mo	South Korea (English)		22/581	48/58	0/16 (3 yr) 0/2 (5 yr)		58
Yamamoto et al[26], 2010		Japan (English)		46/58	57/58		Bleeding 5/58 perforation 2/58	58
Goh et al[27], 2011	Mean 19.39 ± 11.2 mo	South Korea (English)	10/18			3/14		18
Park et al[28], 2012	Mean 41 mo	South Korea, multicenter (2) (English)		23/55				55
Kamada et al[29], 2012	Mean 3.8 yr	Japan (English)	37/46		42/46	1/462	Bleeding 2/46 perforation 2/46	46
Okada et al[30], 2012	Median 36 mo	Japan (English)		85/103	102/103		Bleeding 9/101 perforation 1/101	103
Park et al[31], 2013	Median 24.1 mo (absolute indication group), 30 mo (expanded indication group)	South Korea (English)	91/116		106/116		Bleeding 7/116 perforation 6/116	116
Choi et al[32], 2013	Mean 37.4 mo	South Korea (Korean)	66/82		72/82	3/823		82
Kim et al[33], 2013	Median 34 mo	South Korea, multicenter (6) (English)	54/74	23/74	67/74	4/74	Bleeding 1/74 perforation 3/74	74
Abe et al[34], 2013	Median 76.4 mo	Japan (English)	88/97	62/97	96/97	2/794	Bleeding 4/97 perforation 3/97 delayed perforation 1/97	97
Chung et al[35], 2014	Mean 41.7 ± 22.6 mo	South Korea (Korean)	58/76		64/76	9/64	Bleeding 4/76 perforation 0/76	76
Oka et al[36], 2014	Mean 101.9 ± 38.9 mo	Japan (English)	86/97	60/97			Bleeding 6/97 perforation 1/97	97

¹Curative resection was defined as RM (-), LVI (-), and lesions not deeper than SM 500 um;

²Seven patients who underwent operation after ESD were included;

³Patients who underwent operation or APC ablation were included;

⁴Nineteen patients who underwent operation after ESD were included. ESD: Endoscopic submucosal dissection.