Novel immunological and nutritional-based prognostic index for gastric cancer

Table 5 Univariate and multivariate analyses of prognostic factors including Canton score

Variable	Univariate P value	Multivariate
		HR	95%CI	P value
Age (yr)	0.041			0.051
≤ 65		1
> 65		1.238	0.999-1.536
Sex	0.299
Male
Female
Resectability	< 0.001			0.002
R0		1
R1, R2		1.567	1.204-2.040
Tumor depth	< 0.001
T1, T2
T3, T4
Lymph node	< 0.001
N0
N1-3
Distant metastasis	< 0.001
M0
M1
Pathological stage				0.234
I, II
III, IV	< 0.001
WBC	0.002
≤ 11× 109/L
> 11× 109/L
ALB	< 0.001
≥ 35 g/L
< 35 g/L
PLT	< 0.001			0.795
≤ 300 × 109/L
> 300 × 109/L
CEA	< 0.001
≤ 5 ng/mL
> 5 ng/mL
Histological type	< 0.001
Well
Poor
Blood loss	< 0.001			0.407
≤ 400 mL
> 400 mL
Operative time	0.067
≤ 4 h
> 4 h
Postoperative chemotherapy	0.479
Absent
Present
Postoperative complications	< 0.001
Absent
Present
PLR	< 0.001			0.524
PLR-L
PLR-H
Canton score
0		1
1	0.021	1.076	0.796-1.454	0.633
2	< 0.001	1.554	1.151-2.097	0.004
3	< 0.001	1.643	1.142-2.364	0.007

WBC: White blood cell; ALB: Albumin; PLT: Platelet; CEA: Carcino-embryonic antigen; PLR: Platelet-lymphocyte ratio.