Novel immunological and nutritional-based prognostic index for gastric cancer

Table 2 Relationship between clinicopathological factors, postoperative complications, and prognostic nutritional index

Variable	n (%)	PNI-H	PNI-L	P value
Age (yr)				0.407
≤ 65	445 (70.4)	235	210
> 65	187 (29.6)	92	95
Sex				0.958
Male	413 (65.3)	214	199
Female	219 (34.7)	113	106
Resectability				< 0.001
0	509 (80.5)	285	224
1, 2	123 (19.5)	42	81
Tumor depth				0.006
T1, T2	126 (19.9)	79	47
T3, T4	506 (80.1)	248	258
Lymph node				0.015
N0	193 (30.5)	114	79
N1-3	439 (69.5)	213	226
Distant metastasis				< 0.001
M0	474 (75.0)	266	208
M1	158 (25.0)	61	97
Pathological stage				0.002
I, II	207 (32.8)	125	82
III, IV	425 (67.2)	202	223
WBC				0.279
≤ 11 × 109/L	597 (94.5)	312	285
> 11 × 109/L	35 (5.5)	15	20
ALB				< 0.001
≥ 35 g/L	507 (80.2)	325	182
< 35 g/L	125 (19.8)	2	123
PLT				0.072
≤ 300 × 109/L	484 (76.6)	260	224
> 300 × 109/L	148 (23.4)	67	81
CEA				0.353
≤ 5 ng/mL	547 (86.6)	287	260
> 5 ng/mL	85 (13.4)	40	45
Histological type				0.958
Well	190 (30.1)	98	92
Poor	442 (69.9)	229	213
Blood loss				0.034
≤ 400 mL	423 (66.9)	233	190
> 400 mL	209 (33.1)	94	115
Operative time				0.883
≤ 4 h	253 (40.0)	130	123
> 4 h	379 (60.0)	197	182
Postoperative chemotherapy				0.666
Absent	237 (37.5)	120	117
Present	395 (62.5)	207	188
Postoperative complications				0.488
Absent	551 (87.2)	288	263
Present	81 (12.8)	39	42
Severe complication				0.045
Absent	580 (91.8)	307	273
Present	52 (8.2)	20	32

WBC: White blood cell; ALB: Albumin; PLT: Platelet; CEA: Carcinoembryonic antigen.