Incidence and treatment of brain metastasis in patients with esophageal carcinoma

Table 2 Outcomes of different treatment methods

Study	Number of patients	Treatment	Median survival (mo)	Factors influencing prognosis
Ogawa et al[19]	12	SR + WBRT	9.6	Treatment plan
	24	WBRT	1.8	KPS score
Total	36 (MOS)		3.9
Weinberg et al[20]	4	SR + WBRT	9.6	Liver metastasis
	6	SR	3.8	RPA class
	15	WBRT	3.9
	2	SRT	2.5
Total	27 (MOS)		3.8
Wadhwa et al[23]	20 (MOS)		10.5	None
Kanemoto et al[27]	6	WBRT	1.6	None
	2	SR + WBRT	4.1
	2	SRT	4.0
	1	SRS	18.2
	1	None	0.4
Total	12 (MOS)		2.1
Yoshida[36]	3	SR + WBRT	65.5	None
	7	SR	17.7
	4	SRT	9.5
	3	WBRT	27.1
	(No MOS)

MOS: Overall median survival; KPS: Karnofsky performance status; SR: Surgical resection; SRS: Stereotactic radiosurgery; SRT: Stereotactic radiotherapy; RPA: Recursive partitioning analysis; WBRT: Whole-brain radiation therapy.