Poor oncologic outcomes of hepatocellular carcinoma patients with intra-abdominal infection after hepatectomy

Table 2 Clinicopathological characteristics associated with postoperative intra-abdominal infection and delta-neutrophil-to-lymphocyte ratio

Characteristics	Intra-abdominal infection (No.)		P value	Multivariate analysis	Delta-NLR		P value
	No	Yes		P value	> 1.643	≤ 1.643
Age, yr
< 60	138	19	0.745		108	48	0.268
≥ 60	37	6			32	9
Gender
Male	151	21	0.759		122	48	0.587
Female	24	4			18	9
Drinking
No	136	18	0.525		107	44	0.908
Yes	39	7			33	13
Smoking
No	118	14	0.259		91	39	0.646
Yes	57	11			49	18
HCC family history
No	165	23	0.649		133	53	0.733
Yes	10	2			7	4
HBsAg (+)
No	26	2	0.540		18	10	0.393
Yes	149	23			122	47
Alpha-fetoprotein,
≤ 400 ng/mL	107	18	0.294		91	33	0.349
> 400 ng/mL	68	7			49	24
Hepatic cirrhosis
No	50	2	0.0281	0.0431	36	16	0.734
Yes	125	23			104	41
Child-Turcotte-Pugh
Class A	163	23	0.689		130	53	1.000
Class B	12	2			10	4
Concomitant splenectomy
No	165	19	0.0071	0.0161	127	54	0.565
Yes	10	6			13	3
Tumor nodules
Single	153	21	0.749		119	52	0.242
Multiple	22	4			21	5
Maximal tumor diameters
≤ 5 cm	126	17	0.679		102	38	0.385
> 5 cm	49	8			38	19
Vascular invasion
No	156	18	0.0261	0.0061	119	52	0.242
Yes	19	7			21	5

¹Significant difference. HCC: Hepatocellular carcinoma; HBsAg: Hepatitis B surface antigen.