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©The Author(s) 2015.
World J Gastroenterol. May 7, 2015; 21(17): 5131-5137
Published online May 7, 2015. doi: 10.3748/wjg.v21.i17.5131
Published online May 7, 2015. doi: 10.3748/wjg.v21.i17.5131
Figure 1 Metabolism and excretion of asymmetric dimethylarginine in the liver.
Intracellular asymmetric dimethylarginine (ADMA) is metabolized to citrulline and dimethylamine, a reaction catalyzed by dimethylarginine dimethylaminohydrolase (DDAH). The liver is responsible for the biliary excretion of ADMA. CAT: Cationic amino-acid transporters.
- Citation: Ferrigno A, Di Pasqua LG, Berardo C, Richelmi P, Vairetti M. Liver plays a central role in asymmetric dimethylarginine-mediated organ injury. World J Gastroenterol 2015; 21(17): 5131-5137
- URL: https://www.wjgnet.com/1007-9327/full/v21/i17/5131.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i17.5131