Surgical procedure determination based on tumor-node-metastasis staging of gallbladder cancer

Table 1 AJCC staging classification system of gallbladder carcinoma, 7^th edition

Primary tumor (T)
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Carcinoma in situ
T1 Tumor invades lamina propria or muscle layer
T1a Tumor invades lamina propria
T1b Tumor invades muscle layer
T2 Tumor invades muscle layer, no extension beyond the serosa or into the liver
T3 Tumor perforates the serosa and/or directly invades the liver and/ or one other adjacent organ or structure
T4 Tumor invades main portal vein or hepatic artery or invade two or more extrahepatic organs or structures
Regional lymph nodes (N)
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastases
N1 Metastases to nodes along the cystic duct, common bile duct, hepatic artery, and/or portal vein
N2 Metastases to periarotic, pericaval, and/or celiac artery lymph nodes
Distant metastasis (M)
M0 No distant metastasis
M1 Distant metastasis
Stage 0	Tis	N0	M0
Stage I	T1	N0	M0
Stage II	T2	N0	M0
Stage IIIA	T3	N0	M0
Stage IIIB	T1-3	N1	M0
Stage IVA	T4	N0-1	M0
Stage IVB	Any T	N2	M0
	Any T	Any N	M1