Is cholecystectomy a reasonable treatment option for simple gallbladder polyps larger than 10 mm?

Table 1 Demographic and clinical characteristics of 836 patients n (%)

Characteristics	n = 836
Female	449 (54)
Age (yr)	47 ± 12.3
Indication for surgery1
Size ≥ 10 mm	695 (83)
Increased size2	184 (22)
Abnormal imaging3	59 (7)
Size of the polyp (mm)	11.6 ± 3.5
Number of polyps
1	460 (55.0)
2	128 (15.3)
≥ 3	248 (29.6)
BMI (kg/m2)	26.7 ± 32.1
Total cholesterol (mg/dL)	172.9 ± 33.2
Total bilirubin (mg/dL)	0.8 ± 0.6
ALT (U/L)	32.1 ± 31.3
ALP (U/L)	61.8 ± 25.9
Fasting glucose (mg/dL)	110.3 ± 30.4
CA 19-9 (U/mL)	12.4 ± 38.0
HBsAg positivity	67 (8.0)

¹Repetition was allowed;

²If the polyp size was increased during the follow-up period compared to that in the initial imaging study;

³Gallbladder wall thickness, irregular margin of the polyp, enhancing nodule. GB: Gallbladder; BMI: Body mass index; ALT: Alanine transaminase; ALP: Alkaline phosphatase; CA19-9: Carbohydrate antigen 19-9; HBsAg: Hepatitis B surface antigen.