Decreased STAT4 indicates poor prognosis and enhanced cell proliferation in hepatocellular carcinoma

Figure 3 Relationship between signal transducer and activator of transcription 4 expression and the Ki67 proliferation index in hepatocellular carcinoma. A: Scatterplot of STAT4 expression vs Ki-67 expression; the regression line indicates a correlation based on the Spearman correlation coefficient; B: Kaplan-Meier survival curves of 90 HCC patients stratified into low and high STAT4 expression show a highly significant difference between these groups (P < 0.05, log-rank test using SPSS). STAT4: Signal transducer and activator of transcription 4; HCC: Hepatocellular carcinoma.