Decreased STAT4 indicates poor prognosis and enhanced cell proliferation in hepatocellular carcinoma

Table 3 Contribution of various potential prognostic factors to survival by Cox regression analysis in hepatocellular carcinoma specimens

Parameters	RR	95%CI	P value
Age (yr)	0.156	0.060-0.405	0.069
Gender	1.629	0.843-3.147	0.147
Serum AFP Level (ng/mL)	0.885	0.476-1.647	0.701
Cirrhosis	2.066	0.934-4.572	0.073
Tumor numbers	1.166	0.595-2.288	0.654
HBV	0.742	0.546-1.013	0.057
Maximal tumor size (cm)	0.448	0.460-0.951	0.014
Tumor metastasis	1.732	0.644-4.658	0.277
Microvascular Invasion	0.874	0.430-1.778	0.710
Histological grade	0.343	0.599-0.817	0.0231
STAT4 expression	0.411	0.222-0.758	< 0.0011
Ki67 expression	0.454	0.193-1.065	0.0041

¹The P value was considered significant. Statistical analyses were performed using Long-rank test. HBV: Hepatitis B virus.