Is endoscopic submucosal dissection safe for papillary adenocarcinoma of the stomach?

Table 2 Clinicopathological characteristics of patients with lymph node metastasis

Patient No.	Gender/age	Tumor location	Macroscopic type	Ulceration	Histologic type	Tumor size (mm)	Depth of invasion	Lymphovascular invasion	Pre-treatment ESD indication	Primary treatment
1	F/63	Lower third	IIa	-	PP	35	sm2	+	Out	Op
2	M/58	Lower third	IIa	-	MP + diff.	48	m3	-	In (expanded)	Op
3	F/75	Lower third	I + IIa	-	MP + undiff.	105	sm2	+	Out	Op
4	F/71	Lower third	IIc	+	PP	25	sm2	-	Out	Op
5	M/67	Lower third	I	-	MP + undiff.	23	sm2	-	Out	Op
6	M/64	Lower third	IIc	+	PP	35	sm2	+	Out	Op
7	M/58	Lower third	IIc + III	+	MP + undiff.	55	sm2	+	Out	Op
8	M/68	Lower third	IIa + IIb	-	PP	27	sm2	+	Out	Op
9	F/63	Lower third	IIa	-	MP + diff.	30	sm1	+	In (expanded)	ESD

PP type: Pure papillary type; MP + diff.: Mixed papillary type with differentiated component; MP + undiff.: Mixed papillary type with undifferentiated component; ESD: Endoscopic submucosal dissection; Out: Out-of-ESD indication; In: In ESD indication; Op: Operation.