Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer

doi:10.3748/wjg.v21.i12.3636

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2015; 21(12): 3636-3643
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3636

Table 3 Comparison of neopterin, tryptophan, kynurenine, nitrite, biopterin levels (mean ± SE) in Helicobacter pylori seropositive controls and Helicobacter pylori seropositive colorectal cancer patients

	H. pylori seropositivecontrol group(n = 71)	H. pylori seropositivecolorectal cancer group (n = 78)	P value
Serum neopterin (nmol/L)	7.44 ± 0.61	21.8 ± 3.05	0.0001^a
Tryptophan (nmol/L)	20.71 ± 0.81	14.97 ± 0.79	0.0001^a
Kynurenine (nmol/L)	0.89 ± 0.13	1.28 ± 0.11	0.0001^a
Kynurenine/tryptophan (μmol/mmol)	47.31 ± 5.93	109.65 ± 11.50	0.0001^a
Nitrite (μmol/L)	26.04 ± 2.39	20.41 ± 1.48	0.017^a
Urinary biopterin/creatinine (μmol/mol)	124.65 ± 9.84	120.69 ± 9.98	0.607

^aP < 0.05, Helicobacter pylori (H. pylori) seropositive control vs H. pylori seropositive cancer patients.

Citation: Engin AB, Karahalil B, Karakaya AE, Engin A. Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer. World J Gastroenterol 2015; 21(12): 3636-3643
URL: https://www.wjgnet.com/1007-9327/full/v21/i12/3636.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i12.3636