Surgical outcomes of Korean ulcerative colitis patients with and without colitis-associated cancer

Table 1 Patients’ clinical characteristics according to the presence/absence of cancer n (%)

Variable	Total (n = 415)	UC w/o cancer (n = 368)	UC w/ cancer (n = 47)	P value
Gender, male	212 (51.1)	186 (50.5)	26 (55.3)	0.642
Age at diagnosis (yr)	38.4 ± 0.7	37.9 ± 0.7	42.7 ± 2.6	0.035
Age at surgery (yr)	43.4 ± 0.7	42.2 ± 0.8	52.9 ± 2.1	< 0.001
Period between diagnosis and surgery (yr)	5.0 ± 0.3	4.3 ± 0.3	10.2 ± 1.3	< 0.001
Symptomatic period (yr)	6.0 ± 0.3	5.3 ± 0.3	11.9 ± 1.2	< 0.001
Family history	5 (1.4)	3 (0.9)	2 (4.8)	0.103
Extracolic manifestation	49 (11.8)	45 (12.2)	4 (8.5)	0.632
PSC	5 (1.2)	4 (1.1)	1 (2.1)	0.453
Preoperative steroid therapy	315 (75.9)	297 (80.7)	18 (38.3)	< 0.001
Location, pancolitis	320 (77.1)	284 (77.2)	36 (76.6)	0.025
Left side colitis	88 (21.2)	80 (21.7)	8 (17.0)
Proctitis only	7 (1.7)	4 (1.1)	3 (6.4)
Laparoscopic surgery	46 (11.1)	34 (9.2)	12 (25.5)	0.002
Overall complications	144 (34.7)	133 (36.1)	11 (23.4)	0.103
Early	79 (19.0)	75 (20.4)	4 (8.5)	0.050
Late	65 (15.7)	58 (15.8)	7 (14.9)	0.878
Mortality	5 (1.2)	5 (1.4)	0 (0)	0.925

UC: Ulcerative colitis; PSC: Primary sclerosing cholangitis.