High neutrophil-lymphocyte ratio indicates poor prognosis for acute-on-chronic liver failure after liver transplantation

Table 2 Univariate analysis of variables affecting overall survival after liver transplant

Variable (cut-off value/median/n)	P value	HR (95%CI)
Gender
Male (n = 97)	0.370	1.429 (0.655-3.121)
Female (n = 56)	0.503	0.774 (0.366-1.638)
Age (46 yr)	< 0.001	4.860 (1.857-12.719)
NLR (4.6)	0.288	0.631 (0.270-1.475)
Albumin (35 g/L)	0.163	1.683 (0.809-3.500)
Total bilirubin (337 μmol/L)	0.010	3.251 (1.328-7.958)
MELD score (28)	0.824	0.912 (0.406-2.050)
Child-Pugh score (11)	0.360	1.371 (0.697-2.695)
INR (2.5)	< 0.001	3.823 (1.813-8.062)
Serum creatinine (133 μmol/L)	0.475	1.545 (0.468-5.100)
Pretransplant diabetes (11)	0.686	0.662 (0.090-4.873)
Hypertension before LT (8)	0.629	1.198 (0.576-2.491)
HE (57)	0.286	0.63 (0.27-1.472)
AFP (25 μg/L)

NLR: Neutrophil lymphocyte ratio; PLR: Platelet-lymphocyte ratio; LMR: Lymphocyte-monocyte ratio; AFP: Alpha feto protein; MELD: Model for end-stage liver disease; INR: International normalized ratio; HE: Hepatic encephalopathy.