Azathioprine is essential following cyclosporine for patients with steroid-refractory ulcerative colitis

Table 5 Demographic data and clinical features of patients according to long-term prognosis

	Colectomy (n = 6)	No colectomy (n = 9)	P value
Male:Female (patient no.)	2:4	6:3	P = 0.315 NS
Age at onset (yr; mean ± SE)	17.0 ± 2.8	32.3 ± 4.6	P = 0.063 NS
Age at CyA treatment (yr; mean ± SE)	21.5 ± 3.3	36.6 ± 5.1	P = 0.099 NS
Duration of UC (mo; mean ± SE)	61.8 ± 18.1	62.7 ± 30.6	P = 0.982 NS
CAI score pre-CyA (mean ± SE)	15.7 ± 0.6	14.2 ± 0.7	P = 0.164 NS
CAI score post-CyA (mean ± SE)	5.0 ± 1.0	5.6 ± 1.2	P = 0.732 NS
CRP pre-CyA (mean ± SE)	6.8 ± 2.0	7.7 ± 1.7	P = 0.726 NS
Hb (mean ± SE)	11.3 ± 0.8	10.5 ± 0.7	P = 0.520 NS
Disease extent (patient No.)
Pancolitis: Lt-sided colitis	5:1	7:2	P = 1.000 NS
Clinical course (patient No.)			P = 0.446 NS
Relapse-remitting	4	7
Chronic continuous	1	2
Acute fulminating	1	0
Initial attack	0	0
Endoscopic findings
Poor extensibility (+):(-)	1:5	4:5	P = 0.584 NS
Deep ulcer (+):(-)	4:2	8:1	P = 0.523 NS
Mucosal bleeding (+):(-)	1:5	4:5	P = 0.580 NS

CAI: Clinical activity index; CRP: C-reactive protein; UC: Ulcerative colitis.