Pancreatic cancer stroma: Understanding biology leads to new therapeutic strategies

doi:10.3748/wjg.v20.i9.2237

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Mar 7, 2014 (publication date) through Apr 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2014; 20(9): 2237-2246
Published online Mar 7, 2014. doi: 10.3748/wjg.v20.i9.2237

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Figure 1 Graphical representation of the stromal components and their interactions in pancreatic ductal adenocarcinoma. FAP: Fibroblast activation protein; Smo: Smoothened; SHh: Sonic hedgehog; HGF: Hepatocyte growth factor; PD-L1: Programmed death ligand-1; PD1: Programmed death-1 (receptor); AnxA2: AnnexinA2; TGFβ: Transforming growth factor β; IL-10: Interleukin 10; MDSC: Myeloid derived suppressor cell; Treg: T regulatory cell; TAM: Tumor associated macrophage.

Citation: Rucki AA, Zheng L. Pancreatic cancer stroma: Understanding biology leads to new therapeutic strategies. World J Gastroenterol 2014; 20(9): 2237-2246
URL: https://www.wjgnet.com/1007-9327/full/v20/i9/2237.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i9.2237