Topic Highlight
Copyright ©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2014; 20(8): 1961-1971
Published online Feb 28, 2014. doi: 10.3748/wjg.v20.i8.1961
Table 2 Amsterdam criteria in Lynch syndrome
Amsterdam criteria IAmsterdam criteria II
At least three relatives with CRC; all of the following must be met:At least three relatives with colorectal, endometrial, small bowel, ureter, or renal pelvis cancer; all of the following must be met:
One affected individual is a first degree relative of the other twoOne affected individual is a first degree relative of the other two
At least two successive generations affectedAt least two successive generations affected
At least one CRC diagnosed before the age of 50 yearsAt least one tumor diagnosed before the age of 50 years
Familial adenomatous polyposis has been excludedFamilial adenomatous polyposis has been excluded