Recombinant streptokinase vs phenylephrine-based suppositories in acute hemorrhoids, randomized, controlled trial (THERESA-3)

doi:10.3748/wjg.v20.i6.1594

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Feb 14, 2014 (publication date) through May 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 14, 2014; 20(6): 1594-1601
Published online Feb 14, 2014. doi: 10.3748/wjg.v20.i6.1594

Table 3 Subgroup analyses: 5^th day complete response n (%)

	rSK	Phenylephrine	P value
Type of acute event
Without thrombosis	38/51 (74.5)	15/53 (28.3)	< 0.0001¹
With thrombosis	45/59 (76.3)	21/57 (36.8)	< 0.0001¹
Thrombectomy	1/59 (1.7)	8/57 (14.0)	0.016²
Hemorrhoid classification
External	54/73 (74.0)	22/73 (30.1)	< 0.0001¹
Internal + mixed	29/37 (78.4)	14/37 (37.8)	< 0.0001¹
Prolapse grade
I or II	11/13 (85)	4/7 (57)	0.29²
III or IV	18/24 (75)	10/30 (33)	0.002¹

¹Likelihood ratio χ²;

²Log-rank test. rSK: Recombinant streptokinase.

Citation: Hernández-Bernal F, Castellanos-Sierra G, Valenzuela-Silva CM, Catasús-Álvarez KM, Valle-Cabrera R, Aguilera-Barreto A, Investigators PALSTT3GO. Recombinant streptokinase vs phenylephrine-based suppositories in acute hemorrhoids, randomized, controlled trial (THERESA-3). World J Gastroenterol 2014; 20(6): 1594-1601
URL: https://www.wjgnet.com/1007-9327/full/v20/i6/1594.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i6.1594