An association between Helicobacter pylori and upper respiratory tract disease: Fact or fiction?

Table 5 Detection of Helicobacter pylori in clinical investigations of relationships between Helicobacter pylori and tonsillitis/tonsil hypertrophy

Ref.	Patients(n)	Samples	Methods	Positive results
Unver et al[73]	16	Tonsillar tissue	Urease test	62.5%
Cirak et al[77]	22	Tonsillar tissue	PCR	18.2%
Abdel-Monem et al[80]	20	Tonsillar tissue	Urease test	60%
			PCR	15%
		Blood	ELISA	20%
Najafipour et al[188]	103	Tonsillar tissue	Urease test	48.5%
			PCR	19.4%
Farivar et al[189]	103	Tonsillar tissue	PCR	21.4%
			Histology	18.4%
Jabbari Moghaddam et al[191]	285	Tonsillar tissue	Histology	39.6%
			Urease test	14.0%
		Blood	ELISA	5.2%
Wibawa et al [192]	19	Tonsillar tissue	Culture	15.7%
Nártová et al[193]	89	Tonsillar tissue	PCR	80.9%
Khademi et al[194]	55	Adenotonsillar tissue	Urease test	82%
Aslan et al[195]	52	Tonsil core tissue	Urease test	47%
		Mucosal tissue	Urease test	42%
		Tonsillar tissue	Histology	0%
Lin et al[197]	94	Tonsillar tissue	Urease test	35%
Kusano et al[201]	173	Tonsillar tissue	IHC	72.8%
Kusano et al[202]	55	Tonsillar tissue	IHC	78.2%
Yilmaz et al[203]	50	Blood	ELISA	56%
		Stool	ELISA	50%
		Tonsillar tissue	Urease test	0%
Skinner et al[204]	50	Blood	ELISA	28%
		Tonsillar tissue	Urease test	0%
Jelavic et al[205]	77	Blood	ELISA	79%
		Tonsillar tissue	Urease test	12%
di Bonaventura et al[206]	72	Tonsillar swab	Culture	0%
			IHC	0%
Di Bonaventura et al[207]	72	Tonsillar tissue	PCR	0%

ELISA: Enzyme-linked immunosorbent assay; IHC: Immunohistochemistry; PCR: Polymerase chain reaction.