Reduced hemoglobin and increased C-reactive protein are associated with upper gastrointestinal bleeding

Table 3 Comparison between bleeding (+) and (-) around the day of endoscopy

Laboratory data	Bleeding (-)		Bleeding (+)		Wilcoxon (P value)
	Mean	95%CI	Mean	95%CI
WBC count (/μL)	6370	5946-6795	6700	5613-7786	0.341
Hb (g/dL)	12.8	12.5-13.3	8.4	6.9-9.8	< 0.0001
CRP (mg/dL)	0.50	0.346-0.656	1.37	0.29-2.44	0.009
BUN (mg/dL)	16.4	14.6-18.1	22.5	15.4-29.7	0.096
Cr (mg/dL)	0.83	0.78-0.88	0.92	0.74-1.10	0.302
BUN/Cr	22.0	17.6-26.3	25.1	17.4-32.8	0.196

Bleeding (-), patients not diagnosed as 1a, 1b, 2a, or 2b by Forrest classification; bleeding (+), patients diagnosed as 1a, 1b, 2a, and 2b.Wilcoxon: Wilcoxon signed rank test; CI: Confidence interval; WBC: White blood cell; Hb: Hemoglobin; CRP: C-reactive protein; BUN: Blood urea nitrogen; Cr: Creatinine.