Bifidobacterium infantis attenuates colitis by regulating T cell subset responses

Figure 1 mRNA expression of T cell-related cytokines from mesenteric lymph nodes of normal BALB/c mice fed different doses of Bifidobacterium infantis. A: IL-2; B: IFN-γ; C: IL-12p40; D: IL-4; E: RORγt; F: IL-21; G: IL-23; H: Foxp3; I: IL-10. Control: Mice from control group; Low: Mice treated with low dose Bifidobacterium infantis (B. infantis); High: Mice treated with high dose B. infantis. Real-time RT-PCR was employed to examine the expression of Th1, Th17 and Foxp3⁺ Treg related cytokines. Data are from 5 mice per group. Data are expressed as relative expression and the control group was chosen as the calibrator. Data represent mean ± SE. ^aP < 0.05 vs the control group; ^bP < 0.01 vs the control group. IL: Interleukin; IFN: Interferon.