Non invasive tools for the diagnosis of liver cirrhosis

Table 4 Results of two meta-analyses on the reliability of acoustic radiation force impulse and optimal cut-offs

Ref.	Studies (n)	Etiology	F≥2				F≥3				F = 4
			Cut-off m/s	Se%	Sp%	ROC curve	Cut-off m/s	Se%	Sp%	ROC curve	Cut-off m/s	Se%	Sp%	ROCcurve
Friedrich-Rust et al[166]	8	Mixed	1.34	79	85	0.872	1.55	86	86	0.912	1.80	92	86	0.932
Nierhoff et al[167]	36	Mixed	1.35	-	-	0.841	1.61	-	-	0.891	1.87	-	-	0.911

¹SROC: Area under the Summary Receiver Operating Characteristic;

²AUROC: Area Under Receiver Operating Characteristic. F: METAVIR fibrosis stage.