Protective effects of terminal ileostomy against bacterial translocation in a rat model of intestinal ischemia/reperfusion injury

doi:10.3748/wjg.v20.i47.17905

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 21, 2014; 20(47): 17905-17913
Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17905

Table 2 Incidence and number of bacterial translocations in tissue and blood samples

Group (n = 8)	Liver		Spleen		Kidney		MLN		Blood
Group (n = 8)	Incidence	CFU	Incidence	CFU	Incidence	CFU	Incidence	CFU	Incidence	CFU
Sham	0/8	0 ± 0	0/8	0 ± 0	0/8	0 ± 0	0/8	0 ± 0	0/8	0 ± 0
I/R	6/8^a	841 ± 206.19^a	4/8	33 ± 13.39^a	5/8^a	261 ± 93.66^a	7/8^a	49750 ± 10592.70^a	5/8^a	36 ± 12.25^a
I/R + RA	7/8^a	1316 ± 236.22^a	6/8^a	61 ± 15.42^a	6/8^a	375 ± 88.74^a	8/8^a	64750 ± 8645.29^a	5/8^a	38 ± 11.84^a
I/R + ileostomy	2/8^b	171 ± 112.78^b	2/8	12 ± 7.69^b	3/8	68 ± 33.42^b	3/8^a^b	4850 ± 2510.19^b	2/8	13 ± 5.40

CFU: Colony-forming units; I/R: Ischemia/reperfusion; MLN: Mesenteric lymph nodes; RA: Resection and anastomosis;

^aP < 0.05 vs sham;

^bP < 0.05 vs I/R + RA.

Citation: Lin ZL, Yu WK, Tan SJ, Duan KP, Dong Y, Bai XW, Xu L, Li N. Protective effects of terminal ileostomy against bacterial translocation in a rat model of intestinal ischemia/reperfusion injury. World J Gastroenterol 2014; 20(47): 17905-17913
URL: https://www.wjgnet.com/1007-9327/full/v20/i47/17905.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i47.17905