Genomic landscape of pancreatic neuroendocrine tumors

Table 3 Comparison of copy number alterations by array-based comparative genomic hybridization in recurrent regions in primary tumors and metastases n (%)

Recurrent region	Primary tumor	Metastases	All tumors
n	37	11	48
Gains
01q21.3-q22	4 (10.8)	1 (9.1)	5 (10.4)
03q24	4 (10.8)	0 (0)	4 (8.3)
06p22.2-p22.1	9 (24.3)	4 (36.4)	13 (27.1)
07p21.3-p21.2	6 (16.2)	3 (27.3)	9 (18.8)
07q21.11-q21.12	2 (5.4)	3 (27.3)	5 (10.4)
08q24.3	4 (10.8)	1 (9.1)	5 (10.4)
09q34.11	6 (16.2)	3 (27.3)	9 (18.8)
11q13.1-q13.2	2 (5.4)	2 (18.2)	4 (8.3)
16p11.2	2 (5.4)	3 (27.3)	5 (10.4)
16q22.1	5 (13.5)	1 (9.1)	6 (12.5)
17p13.1	7 (18.9)	3 (27.3)	10 (20.8)
18q12.1	5 (13.5)	0 (0)	5 (10.4)
19p13.3	4 (10.8)	0 (0)	4 (8.3)
22q13.33	1 (2.7)	2 (18.2)	3 (6.3)
Losses
08q24.3	3 (8.1)	0 (0)	3 (6.3)
11q13.1-q13.2	2 (5.4)	0 (0)	2 (4.2)
16p11.2	2 (5.4)	0 (0)	2 (4.2)
16q22.1	1 (2.7)	0 (0)	1 (2.1)
17p13.1	1 (2.7)	0 (0)	1 (2.1)
22q13.33	0 (0)	1 (9.1)	1 (2.1)