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©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 7, 2014; 20(45): 17037-17048
Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17037
Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17037
Table 1 Performance of tumor necrosis factor receptor-associated protein 1 staining in distinguishing progressors from non-progressors
| Using TRAP1 expression in different histologic grades as a biomarker (n) | Controls (n) | AUC value | Sensitivity at | |
| 90% specificity | 80% specificity | |||
| LGD (29) | Non-progressors (38) | 0.86 | 69% | 79% |
| HGD (14) | Non-progressors (38) | 0.97 | 86% | 100% |
| Cancer (17) | Non-progressors (38) | 0.87 | 82% | 88% |
| Progressor rectal tissue (39) | Non-progressors (38) | 0.71 | 41% | 59% |
| Highest TRAP1 in dysplasia (36) | Non-progressors (38) | 0.94 | 86% | 94% |
| Highest overall TRAP1 (42) | Non-progressors (38) | 0.88 | 76% | 83% |
- Citation: Chen R, Pan S, Lai K, Lai LA, Crispin DA, Bronner MP, Brentnall TA. Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer. World J Gastroenterol 2014; 20(45): 17037-17048
- URL: https://www.wjgnet.com/1007-9327/full/v20/i45/17037.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i45.17037