Focus on emerging drugs for the treatment of patients with non-alcoholic fatty liver disease

doi:10.3748/wjg.v20.i45.16841

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Dec 7, 2014 (publication date) through Apr 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2014; 20(45): 16841-16857
Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16841

Table 1 Main treatments and emerging drugs for patients with non-alcoholic fatty liver disease

Lifestyle intervention	Anti-obesity drugs	Glucose control	Lipid-lowering drugs	Cytoprotectiveagents	Other drugs	Emerging drugs and new horizons
Diet	Orlistat	Insulin-sensitizing agents	Statins, fibrate and ezetimibe	Ursodeoxycholic acid	Probiotics	Inhibitors of caspases
Weight loss	Cannabinoid agonists	New anti-diabetic drugs	Probucol	Anti-oxidants	Anti-TNF-α monoclonal antibodies	Adenosine system drugs
Physical exercise		Renal glucose transporters blockers		Herbal products	Anti-hypertensive drugs	PPAR agonists
Surgery (not treated)					Pentoxifylline	Peripheral cannabinoid agonists
					Iron depletion	Farnesoid X receptor agonists
						Thyroid hormone analogues

TNF: Tumor necrosis factor; PPAR: Peroxisome proliferator-activated receptors.

Citation: Federico A, Zulli C, de Sio I, Del Prete A, Dallio M, Masarone M, Loguercio C. Focus on emerging drugs for the treatment of patients with non-alcoholic fatty liver disease. World J Gastroenterol 2014; 20(45): 16841-16857
URL: https://www.wjgnet.com/1007-9327/full/v20/i45/16841.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i45.16841