Xeroderma pigmentosum group D polymorphisms and esophageal cancer susceptibility: A meta-analysis based on case-control studies

Table 2 Results of the meta-analysis for the xeroderma pigmentosum group D Asp312Asn polymorphism and esophageal cancer susceptibility

Study group	Co-dominant model						Dominant model			Recessive model			Additive model
	Asp/Asn vs Asp/Asp			Asn/Asn vs Asp/Asp			Asn/Asn+Asp/Asn vs Asp/Asp			Asn/Asn vs Asp/Asn+Asp/Asp			(2Asn/Asn+Asp/Asn) vs 2(Asp/Asn+Asn/Asn+Asp/Asp)
	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph	OR (95%CI)	P	Ph
Total	1.17 (1.02, 1.33)	0.03	0.97	1.30 (1.00, 1.70)	0.05	0.75	1.18 (1.04, 1.34)	0.01	0.98	1.17 (0.91, 1.50)	0.22	0.71	1.10 (1.00, 1.21)	0.06	1.00
Cancer type
ESCC	1.09 (0.91, 1.31)	0.35	0.95	0.99 (0.54, 1.79)	0.96	0.48	1.09 (0.91, 1.30)	0.35	0.99	0.93 (0.53, 1.63)	0.79	0.40	1.06 (0.90, 1.24)	0.49	0.99
EADC	1.26 (1.03, 1.53)	0.02	0.97	1.40 (1.04, 1.89)	0.03	0.93	1.29 (1.07, 1.55)	0.01	0.99	1.24 (0.94, 1.64)	0.13	0.90	1.12 (0.99, 1.28)	0.07	0.98
Ethnicity
Chinese	1.08 (0.88, 1.33)	0.45	0.88	2.08 (0.57, 7.60)	0.27	0.66	1.10 (0.90, 1.35)	0.36	0.93	2.06 (0.57, 7.51)	0.27	0.65	1.10 (0.91, 1.33)	0.34	0.98
Non-Chinese	1.23 (1.03, 1.47)	0.02	0.95	1.27 (0.97, 1.67)	0.08	0.54	1.24 (1.05, 1.47)	0.01	0.93	1.14 (0.89, 1.47)	0.31	0.53	1.10 (0.98, 1.23)	0.11	0.92

ESCC: Esophageal squamous cell carcinoma; EADC: Esophageal adenocarcinoma; Ph: P value of the Q-test for heterogeneity.