Boceprevir is highly effective in treatment-experienced hepatitis C virus-positive genotype-1 menopausal women

Table 2 Univariate and multivariate analysis for factors predicting sustained virological response

Variables	Univariate analysis OR (95% CI)	P value	Multivariate analysis OR (95% CI)	P value
Age (yr)	1.006 (0.916-1.105)	0.900
Age at menopause	1.150 (0.931-1.450)	0.195
Previous response	2.662 (0.957-6.881)	0.043	2.927 (0.931-9.206)	0.066
Histological grading	0.894 (0.605-1.322)	0.576
Histological staging	0.982 (0.586-1.645)	0.946
Fibrosis	1.667 (0.528-5.265)	0.384
Liver stiffness	0.986 (0.895-1.086)	0.774
Cirrhosis	1.111 (0.155-7.974)	0.917
BMI	1.000 (0.825-1.212)	1.000
HCV RNA > 800.000 IU/mL	0.519 (0.120-2.248)	0.381
RVR	1.200 (0.070-20.429)	0.900
1 log decline at week 4	3.733 (1.676-12.658)	0.034	0.961(0.194-4.757)	0.961
RVR BOC	7.347 (2.156-25.035)	0.001	6.794 (1.596-21.644)	0.010
ALT (IU/mL)	0.996 (0.977-1.014)	0.645
Platelets (× 103/mm3)	1.000 (1.000-1.000)	0.165
HOMA	0.907 (0.533-1.544)	0.719

BMI: Body mass index; HCV: Hepatitis C virus; ALT: Alanine aminotransferase.