Advances in non-surgical management of primary liver cancer

Table 1 American Joint Committee on Cancer Tumor Node Metastasis staging system

Stage	Tumor	Node	Metastasis
Stage I	T1: Solitary tumor without vascular invasion	N0: No regional lymph	M0: No distant metastasis
Stage II	T2: Solitary tumor with vascular invasion or multiple tumors, size < 5 cm	Node metastasis
StageIIIA	T3: Multiple tumors with size > 5 cm or tumor involving a major branch of the portal or hepatic vein(s)
Stage IIIB	T4: Tumor that invades adjacent organs other than the gallbladder or perforates visceral peritoneum
Stage IIIC	Any T	N1: Regional lymph node metastasis
Stage IV	Any T	Any N	M1: Distant metastasis