Colon capsule endoscopy: Current status and future directions

Table 4 Diagnostic accuracy of colon capsule endoscopy for the detection of significant colon polyps (≥ 6 mm or ≥ 3 polyps)

Ref.	Year published	Colon capsule	Number of patients included	Sensitivity	Specificity	PPV	NPV
Schoofs et al[3]	2006	CCE-1	36	77%	70%	59%	84%
Eliakim et al[37]	2006	CCE-1	84	50%	83%	40%	88%
Van Gossum et al[10]	2009	CCE-1	320	64%	84%	-	-
Gay et al[39]	2010	CCE-1	126	87.5%	76%	79%	85%
Pilz et al[38]	2010	CCE -1	56	79%	54%	63%	71%
Sacher-Huvelin et al[11]	2010	CCE-1	545	39%	88%	47%	85%
Eliakim et al[4] second gen	2009	CCE-2	98	89%	76%	46%	97%
Spada et al[8]	2011	CCE-2	109	84%	64%	-	-
Rex et al[6]	2013	CCE-2	689	81%	93%	-	-

CCE-1: First generation colon capsule endoscopy; CCE-2: Second generation colon capsule endoscopy; PPV: Positive predictive value; NPV: Negative predictive value.