Diagnostic value of interleukin-8 in colorectal cancer: A case-control study and meta-analysis

Table 1 Characteristics of included studies

Study	Country	Design	Male	Age (yr)	No. of participants	Sensitivity	Specificity	TP	FP	FN	TN	QUADAS
			(%)									score
Pengjun et al[11], 2013	China	Case-control	52.4	31-74	149 CRC, 93 colorectal adenoma, 69 controls	0.869	0.971	149	2	23	69	12
				(mean 58.0)
Kantola et al[18], 2012	Finland	Case-control	51.0	Mean 67.9	148 CRC, 86 controls	0.809	0.821	115	18	27	84	12
Bünger et al[10], 2012	Germany	Case-control	52.3	40.5-99.1	164 CRC, 34 colorectal adenomas, 119 controls	0.220	0.900	81	6	287	52	12
				(mean 69.6)
Bünger et al[19], 2011	Germany	Case-control	52.0	38-88	50 CRC, 50 controls	0.280	0.940	50	3	129	50	12
				(mean 71.2)
Kaminska et al[20], 2005	Poland	Case-control	49.0	32-82	157 CRC, 50 controls	0.883	0.580	157	36	21	50	11
Current study	China	Case-control	52.1	Mean 55.4	48 CRC, 37 controls	0.854	0.541	41	17	7	20	12

TP: True positive; FP: False positive; TN: True negative; FN: False negative; QUADAS: Quality assessment of diagnostic accuracy studies; CRC: Colorectal cancer.