Potent antiviral therapy improves survival in acute on chronic liver failure due to hepatitis B virus reactivation

Table 3 Independent prognostic factors for mortality (and liver transplantation) in severe acute exacerbation of chronic hepatitis B[22]

Parameters	Chan et al[40] 2002, J Viral Hepatol	Yuen et al[19] 2003, Clin Infect Dis	Chien et al[49] 2003, J Hepatol	Tsubota et al[45] 2005, J Gastroenterol Hepatol	Kumar et al[38] 2006, Dig Dis Sci
Age	N/A	N/A	N/A	N/A	N/A
Sex	N/A	N/A	N/A	N/A	N/A
Albumin	N/A	N/A	Low	N/A	N/A
Bilirubin	High	High	High	High	High
Prothrombin Time	N/A	Prolonged	Prolonged	Prolonged	Prolonged
ALT	N/A	N/A	N/A	N/A	High
Platelet count	Low	Low	Low	N/A	Not studied
HBeAg	N/A	N/A	N/A	N/A	High
HBV DNA	Not studied	N/A	N/A	N/A	High
Creatinine	N/A	N/A	N/A	Not studied	Not studied
AFP	Not studied	N/A	N/A	N/A	Not studied
Cirrhosis	Not studied	Present	N/A	Present	Not studied
Ascites	Not studied	Not studied	Present	N/A	Not studied
CTP	Not studied	Not studied	High	High	Not studied

AFP: α-fetoprotein; N/A: Not applicable; HBeAg: Hepatitis B e antigen; ALT: Alanine aminotransferase; HBV: Hepatitis B virus; CTP: Child-Turcotte-Pugh.