Effect of Danshao Huaxian capsule on Gremlin and bone morphogenetic protein-7 expression in hepatic fibrosis in rats

doi:10.3748/wjg.v20.i40.14875

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2014; 20(40): 14875-14883
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14875

Table 2 Comparison of levels of hyaluronic acid, hydroxyproline and transforming growth factor β1 in liver homogenates

Group	n	HA (ng/g)	Hyp (μg/g)	TGF-β1 (μg/g)
A	15	1449.93 ± 121.89	318.20 ± 9.71	284.20 ± 18.32
B	13	8803.30 ± 200.57^b	617.77 ± 8.52^b	736.30 ± 24.40^b
C	15	7558.40 ± 161.88^b^d	530.27 ± 11.88^b^d	651.13 ± 15.75^b^d
D	14	5249.21 ± 111.92^b^d^f	490.00 ± 8.13^b^d^f	523.14 ± 21.29^b^d^f
E	15	4050.73 ± 122.18^b^d^f^h	464.07 ± 13.09^b^d^f^h	441.86 ± 23.18^b^d^f^h

Data are expressed as mean ± SD. A: Normal group; B: Model group; C: Natural recovery group; D: Low dose Danshao Huaxian capsule (DHC) treated group; E: High dose DHC treated group.

^bP < 0.01 vs group A;

^dP < 0.01 vs group B;

^fP < 0.01 vs group C;

^hP < 0.01 vs group D.

Citation: Zhao XK, Cheng ML, Wu RM, Yao YM, Mu M, Zhu JJ, Zhang BF, Zhou MY. Effect of Danshao Huaxian capsule on Gremlin and bone morphogenetic protein-7 expression in hepatic fibrosis in rats. World J Gastroenterol 2014; 20(40): 14875-14883
URL: https://www.wjgnet.com/1007-9327/full/v20/i40/14875.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i40.14875