Non-invasive diagnosis of alcoholic liver disease

Table 4 Typical routine blood tests in alcoholic liver disease

Parameter	Pathologic	F0-2(<8 kPa)	F3-4(>8 kPA)	Mean F0-2	Mean F3-4
GOT (U/L)	> 50	56.9%	78.4%	89.5	135.4
GPT (U/L)	> 50	50.6%	48.6%	75.0	70.6
GGT (U/L)	> 60	69.4%	97.3%	238.8	792.8
AP (U/L)	> 130	9.0%	50.5%	90.2	152.0
Bilirubin total (mg/dL)	> 1.3	7.8%	43.2%	0.8	2.9
INR	> 1.27	0.8%	25.9%	1.2	1.1
Platelets (/nL)	< 150	17.5%	48.6%	222.5	172.0
Ferritin (ng/mL)	> 1000	15.6%	35.4%	524.7	830.7
Ferritin (ng/mL)	> 400	39.8%	60.4%	524.7	830.7
Triglycerides (mg/dL)	> 200	29.4%	25.7%	187.9	206.5
Cholesterine (mg/dL)	> 200	65.5%	52.8%	225.7	202.8
Albumin (g/dL)	< 3.8	4.3%	37.3%	5.4	5.2
Transferrin (g/A)	< 2	14.8%	38.6%	2.5	2.2
Transferrin saturation	> 45%	32.0%	45.9%	42.0	48.0
Hepatic steatosis (US)	> 1	70.9%	82.4%	1.9	2.2
Spleen size (cm)	> 11.5	7.5%	35.5%	9.6	11.1
Ascites	> 0	0.0%	20.7%	0.0	0.2
Signs of cirrhosis (US)	> 0	1.7%	43.9%	0.0	0.4
Liver stiffness (final)	> 8	0.0%	100.0%	4.8	32.7
CAP (dB/m)	> 300	42.2%	64.9%	287.0	308.3

The table shows percentage and means of pathologic routine blood tests in patients with alcoholic liver disease (ALD) (preliminary data from Salem Medical Center n = 275) solely characterized by non-invasive transient elastography (TE). US: Ultrasonography; CAP: Controlled attenuation parameter (Echosens); GGT: γ-glutamyl transpeptadase; GOT: Glutamic-oxal(o)acetic transaminase; GPT: Glutamate pyruvate transaminase; AFP: α-fetoprotein; AP: Alkaline phosphatase.