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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 28, 2014; 20(40): 14581-14588
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14581
Table 1 Risk factors for anticancer chemotherapy-related hepatitis B virus reactivation
CategoriesRisk factorsRef.
Host factorsMale gender Young age Elevated baseline ALT[8] [8] [63]
Tumor- or treatment-related factorsLymphoma Hematologic malignancies Brease cancer Glucocorticoid use Anthracycline use Rituximab-based regimen Hematopoietic stem cell transplantation[6,8] [8,64] [6] [6,16] [6] [17,29] [65]
Viral factorsHigh pre-chemotherapy viral load Positive HBeAg Presence of precore mutant Negative or low titer of HBsAb (in case of occult/past infection)[66] [8,67] [25,68] [17]